Effect Of Allopurinol On Germ Cell Apoptosis Following Testicular Ischemia-Reperfusion Injury In A Rat

 02.07.2008 06:18   medicalnewstoday.com

ORLANDO, FL (UroToday.com) - It is recognized that apoptosis is involved in germ cell loss following testicular ischemia-reperfusion (IR) injury. Allopurinol is as a free radical scavenger which prevents tissue damage caused by reperfusion and oxygenation after ischemia. The authors have investigated the ability of allopurinol to effect testicular injury after torsion. Testicular ischemia in rats led to histological damage in the ipsilateral testis.

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